Studies of Thiomorpholine Derivatives. I. : Synthesis of 2-Substituted-3-oxoperhydro-2H-1, 4-thiazine-5-carboxylic Acids and Their Reaction with Thionyl Chloride containing Sulfuryl Chloride
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منابع مشابه
Synthesis and Biological Evaluation of 2-isonicotinyl 3, 5-diaryl -2h-(3-tetrazolium) Chloride Derivatives
A synthesis of 2-Isonicotinyl 3, 5-diaryl -2H-(3-tetrazolium) chloride (5) was performed starting from isonicotinic hydrazide (1). The treatment of 1 with various substituted aromatic aldehydes afforded the corresponding Schiff’s bases 3. The Schiff’s bases are converted into a series of aryl formazan via diazocoupling which underwent cyclization in the presence of H2O2 and KMnO4 to give substi...
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The resistance of antimicrobials has become a global hazard with the irrational use of antibiotics. Infection of drug-resistance bacteria seriously threatens human health. Currently there is an urgent need for the development of novel antimicrobial agents with new mechanisms and lower levels of toxicity. In this paper, a series of (S,Z)-4-methyl-2-(4-oxo-5-((5-substitutedphenylfuran-2-yl) methy...
متن کاملSynthesis and Antimicrobial Activity of Some 2-[(4-Substituted-Phenyl-3-Chloro-Azetidin-2-One)-5-(2'-Methylamino-4-Phenyl-1', 3'-Thiazolyl-]-1, 3,4-Thiadiazoles
A new 2-[(4-substituted-phenyl-3-chloroazetidin-2-one)-5-(2'-methylamino 4-phenyl-1', 3'-thiazolyl-]-1, 3, 4-thiadiazoles, 5(a-n) were synthesized from 2-substituted-benzylideneamino-5-[2'-methylamino-4'-phenyl-1',3'-thiazolyl]-1,3, 4-thiadiazole, 4(a-n) using 2-amino-4phenyl-1, 3-thiazole as a starting material. The synthesised compounds have been screened in vitro for their antimicrobial acti...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1970
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.90.5_570